01 - Pat tilapia fillets dry with paper towels. Combine chili powder, cumin, smoked paprika, garlic powder, salt, and black pepper in a small bowl. Season both sides of tilapia with spice mixture, then drizzle with olive oil and lime juice.
02 - Heat a large nonstick skillet over medium-high heat. Cook the fillets for 3 to 4 minutes per side until golden brown and cooked through. Let rest for 2 minutes, then flake into bite-sized pieces.
03 - Combine cabbage, carrots, cilantro, lime juice, olive oil, salt, and pepper in a large bowl. Toss thoroughly to coat evenly.
04 - Whisk together sour cream (or Greek yogurt), lime juice, hot sauce (if using), and salt in a small bowl until smooth and creamy.
05 - Heat tortillas in a dry skillet for 30 seconds per side or microwave wrapped in damp paper towels for 30 seconds.
06 - Layer slaw and flaked tilapia onto warmed tortillas. Drizzle with crema. Top with sliced avocado, fresh cilantro leaves, and a squeeze of lime juice.
07 - Serve immediately while fish is warm and tortillas are pliable.